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A case report: A rare case of icteric variant of Stauffer's syndrome
P Abiharan1, B Balagobi2, S Gobishangar2
1University Surgical Unit, Teaching Hospital Jaffna, Sri Lanka.
Introduction:
Stauffer's syndrome is a rare paraneoplastic non metastatic hepatic dysfunction related to renal cell carcinoma. It is characterized by elevated alkaline phosphatase, erythrocyte sedimentation rate, a-2-globulin, y-glutamyl transferase, thrombocytosis, prolongation of prothrombin time and hepatosplenomegaly, in the absence of hepatic metastasis. A rare variant of it with cholestatic jaundice is described in four cases so far in literature.
Clinical Presentation:
We present a case of a patient presented with features of cholestatic jaundice who was found to have a left sided renal cell carcinoma in the work up.
Discussion:
This case illustrates the importance of considering paraneoplastic syndromes in mind when working up for patients presenting with hepatic dysfunctions without identifiable causes.
Conclusion:
This may result in early identification and intervention which will result in better outcome and prolong survival rate.
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