Related Experiment Video

Updated: Jul 24, 2025

Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism
11:37

Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism

Published on: July 28, 2017

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Not all 2',4'-bridged modifications stabilize DNA/RNA duplexes

Tomoka Akita1,2, Elisa Tomita-Sudo2, Shin Itoh1

  • 1Faculty of Frontiers of Innovative Research in Science and Technology, Konan University, Kobe, Japan.

Nucleosides, Nucleotides & Nucleic Acids
|July 10, 2023
PubMed

Keywords:
Bridged nucleic acidsantisense oligonucleotidesbinding affinitylocked nucleic acidsthermodynamic stability

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