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Dentine surface modification and remineralization induced by bioactive toothpastes
Maria Giovanna Gandolfi1, Paola Taddei2, Fausto Zamparini1
1Laboratory of Green Biomaterials and Oral Pathology, School of Dentistry, Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.
International Journal of Dental Hygiene
|July 10, 2023
Summary
Toothpastes containing arginine and calcium carbonate promote significant dentine remineralization. These formulations enhance mineral content and resist acid attacks, offering superior protection against demineralization.
Area of Science:
- Dental Biomaterials Science
- Surface Chemistry
- Mineralization Studies
Background:
- Dentine demineralization poses a significant challenge in restorative dentistry.
- Evaluating the efficacy of various toothpaste formulations in remineralizing dentine is crucial for developing effective oral care products.
Purpose of the Study:
- To assess the morpho-chemical changes and mineralization variations on dentine surfaces after treatment with different toothpastes.
- To compare the remineralization potential and acid resistance of various toothpaste formulations.
Main Methods:
- Environmental-scanning-electron-microscopy (ESEM) with energy-dispersive-X-ray-spectrometry (EDX) and Fourier-transform-infrared-spectroscopy (FTIR) with attenuated total-reflectance (ATR) were employed.
- Ca/P, Ca/N, and P/N ratios were calculated from EDX data to assess mineralization.
- IR spectroscopy was used to evaluate CaP/collagen and carbonate/collagen ratios for remineralization assessment.
Main Results:
- All tested toothpastes left residuals on the dentine surface.
- Arginine & Calcium carbonate toothpaste demonstrated the highest Ca/P ratio post-treatment and after acid attack.
- Arginine & Calcium carbonate and HA & Citrate toothpastes showed higher remineralization activity and resistance to demineralization.
Conclusions:
- Toothpastes that adhere better to the dentine surface, particularly those with arginine and calcium carbonate, are more effective in promoting remineralization.
- The remineralized calcium phosphate phase forms an integral bond with the dentine structure.
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