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Published on: March 23, 2019
A Case of Urinary Tract Infection Caused by Multidrug Resistant Streptococcus mitis/oralis
Baohu Zhang1, Jie Zhou1, Guancong Xie2
1Department of Clinical Laboratory, Pingshan General Hospital, Southern Medical University (Pingshan District People's Hospital of Shenzhen), Shenzhen, Guangdong, People's Republic of China.
Abstract:
S. mitis/oralis has been previously reported in isolated cases of bacterial endocarditis and liver abscesses. Its presence in urine is generally considered a contaminant. A 66-year-old male patient was admitted to the hospital due to recurrent chest tightness and four-year history of exertional dyspnea. On the second day of admission, the patient presented with urgent and frequent urination, as well as dysuria. Both initial and subsequent urine cultures showed S. mitis/oralis infection, with polymorphonuclear leukocyte phagocytosis observed in the second sample. MALDI-TOF results confirmed the isolated strain as S. mitis/oralis. Drug susceptibility testing revealed multidrug resistance to penicillin, ceftriaxone, cefepime, levofloxacin, ofloxacin, and tetracycline, but sensitivity to quinupristin/dalfopristin, vancomycin, and linezolid. The clinician then prescribed vancomycin for anti-infective treatment, which proved effective. Keywords: S. mitis/oralis, UTI, MDR, phagocytosis.
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