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Coronavirus

Coronavirus

Coronaviruses, including the severe acute respiratory syndrome coronavirus (SARS-CoV), are enveloped viruses characterized by their single-stranded, positive-sense RNA genome and helical nucleocapsid structure. The hallmark of these viruses is their club-shaped spike (S) glycoproteins that protrude from the viral envelope, facilitating attachment to host cells. Typically, coronaviruses infect the upper respiratory tract, often causing mild or asymptomatic disease. However, certain strains like...

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Updated: Jul 20, 2026

Isolation of Exosomes from the Plasma of HIV-1 Positive Individuals

Isolation of Exosomes from the Plasma of HIV-1 Positive Individuals

Published on: January 5, 2016

Convalescent Plasma in COVID-19.

Ranjit S Banwait¹, Joshua K Salabei¹, Troy J Fishman¹

¹University of Central Florida/ HCA Healthcare North Florida Regional Medical Center.

HCA Healthcare Journal of Medicine

|July 10, 2023

Summary

Convalescent plasma (CP) is a potential treatment for COVID-19, offering an option when no definitive therapies exist. This review examines CP

Keywords:

COVID-19 COVID-19 serotherapy Coronavirus SARS-CoV-2 emerging communicable diseases intravenous immunoglobulins passive immunization plasma

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Last Updated: Jul 20, 2026

Isolation of Exosomes from the Plasma of HIV-1 Positive Individuals

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Published on: January 5, 2016

Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19

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Enrichment of Astrocyte-Derived Extracellular Vesicles from Human Plasma

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Published on: August 3, 2022

Area of Science:

Infectious Diseases
Immunology
Virology

Background:

The COVID-19 pandemic caused by SARS-CoV-2 has created a global health crisis.
Effective treatments are urgently needed to combat the spread of SARS-CoV-2.
No definitive antiviral treatment currently exists for COVID-19.

Purpose of the Study:

To review the historical use of convalescent plasma (CP) in treating infections.
To explore the mechanism of action of CP.
To summarize current experiences with CP for COVID-19 treatment.

Main Methods:

Literature review of historical CP usage.
Analysis of CP's therapeutic mechanisms.
Compilation of data on CP application in COVID-19.

Main Results:

Convalescent plasma has a history of use in various infectious diseases.
CP contains antibodies that may neutralize pathogens.
Early experiences with CP in COVID-19 are being documented.

Conclusions:

Convalescent plasma is a viable therapeutic option for COVID-19.
Further research is needed to fully establish CP efficacy and safety.
CP represents a promising approach in the absence of specific treatments.