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Pancoast Syndrome Due to High Grade Anaplastic Tumor
Christian Almanzar1, Seth Maxwell1, Mauricio Gomez1
1HCA Healthcare/USF Morsani College of Medicine GME Programs, Brandon Regional Hospital, Brandon, FL.
HCA Healthcare Journal of Medicine
|July 10, 2023
Summary
Pancoast syndrome, a complication of superior sulcus tumors, presents with pain and neurological issues. This case highlights anaplastic cells as a rare cause of Pancoast syndrome, emphasizing diverse origins of this condition.
Area of Science:
- Oncology
- Neurology
- Pulmonology
Background:
- Pancoast tumors originate in the superior sulcus of the lung.
- Pancoast syndrome involves shoulder/arm pain, Horner's syndrome, and neurological deficits due to mass effect.
Observation:
- The patient presented with Pancoast syndrome.
- The underlying malignancy was a poorly differentiated neoplasm with anaplastic cells.
Findings:
- Anaplastic cells, though rare, can cause Pancoast syndrome.
- Adenocarcinoma is the most common lung cancer cause of Pancoast syndrome.
Implications:
- Highlights the importance of considering diverse malignancies in Pancoast syndrome diagnosis.
- Standard non-small cell lung cancer treatments are applicable.
- Further research into rare causes of Pancoast syndrome is warranted.

