Related Experiment Video
Updated: Jul 24, 2025

08:41
Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
Published on: November 5, 2021
2.8K
The Coronaviruses: Past, Present, Future
Kimball Kaufman1, Shobhit Keswani1, Cristobal Cintron2
1MountainView Hospital, Internal Medicine Residency, Sunrise Health GME Consortium, Las Vegas, NV.
HCA Healthcare Journal of Medicine
|July 10, 2023
Summary
The novel coronavirus pandemic is a unique global event, unlike the 1918 Spanish flu. Despite advanced medical knowledge and infrastructure, it severely impacts economies and populations worldwide.
Area of Science:
- Epidemiology
- Global Health
- Medical History
Background:
- The current coronavirus pandemic presents a unique global health crisis.
- Historical comparison with the 1918 Spanish flu highlights differences in societal impact despite advanced medical knowledge.
- The virus demonstrates a capacity for widespread devastation across developed nations with robust infrastructure.
Discussion:
- Analysis of the coronavirus pandemic from historical and clinical viewpoints.
- Examining the virus's profound disruption to global economies and populations.
- Highlighting the unprecedented nature of this pandemic in the modern era.
Key Insights:
- The coronavirus pandemic's global impact transcends geographical boundaries.
- Despite advanced medical technology, the virus poses a significant threat.
- A comprehensive understanding requires integrating historical context and clinical data.
Outlook:
- The need for a continually updated knowledge base on the virus.
- Importance of a multidisciplinary approach involving historical and clinical perspectives.
- Preparing for future global health challenges through shared knowledge.
Keywords:
COVID-19MERSSARSSARS-CoVSARS-CoV-2coronavirus infectionsemerging communicable diseasesinfectious disease medicinepandemicssevere acute respiratory syndrometherapeutics/drug therapyMore Related Videos
Related Concept Videos
Viral Mutations
32.5K
A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
32.5K
History of Microbiology
242
Microbiology, a scientific field dedicated to the study of microorganisms, has undergone profound development since its inception in the 17th century. Its history is marked by key discoveries and technological advancements that have shaped our understanding of life at the microscopic level and transformed medicine, agriculture, and industry.Early Foundations of MicrobiologyThe early foundations of microbiology were built on groundbreaking observations and the development of pioneering...
242
What are Viruses?
115.3K
Overview
115.3K
Viruses with RNA Genomes
57
RNA viruses are categorized into positive-strand, negative-strand, or double-stranded groups based on their genomic structure and replication mechanisms. This classification dictates how they exploit host cellular machinery for protein synthesis and replication. Some RNA viruses also utilize reverse transcription as part of their life cycle, further diversifying their replication strategies.Positive-Strand RNA VirusesPositive-strand RNA viruses have genomes that function directly as messenger...
57
Viruses of Archaea
31
Archaeal viruses play a crucial role in the ecosystems of extremophilic archaea, particularly those belonging to the phyla Euryarchaeota and Crenarchaeota. By shaping host evolution and facilitating gene transfer, these viruses influence microbial communities and contribute to genetic diversity in extreme environments. The archaea they infect thrive in acidic hot springs and hydrothermal vents characterized by high temperatures and low pH. Archaeal viruses exhibit remarkable structural...
31
Introduction to Virus
94
Viruses are unique biological entities that blur the boundary between living and non-living systems. Although they lack cellular structure and metabolic processes, they can exhibit characteristics of life when infecting a host. Their defining feature is a nucleic acid core, composed of either DNA or RNA, encapsulated within a protein coat called a capsid. This simple structure allows them to invade host cells and use their machinery for replication efficiently.Viral Structure and...
94

