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Effect of Saengmaeksan on Fatigue, Liver Function, and Immunity Combined with High-Intensity Training
Shi Juan1, Jae-Hoon Lee2, Se-Jong Won3
1Xi'an FanYi University, Shaanxi 710105, China.
Journal of Immunology Research
|July 10, 2023
Summary
Saengmaeksan (SMS) may reduce fatigue and improve liver function and immunity in athletes undergoing high-intensity training. This study found SMS intake lowered ammonia, AST, ALT, and IgM, while increasing IgA.
Area of Science:
- Sports Science
- Human Physiology
- Herbal Medicine
Background:
- Saengmaeksan (SMS), a traditional herbal drink, is known for its potential benefits in combating fatigue and enhancing liver and immune functions.
- High-intensity training can negatively impact fatigue, liver function, and immunity, necessitating interventions to mitigate these effects.
- Understanding the physiological responses to herbal supplementation during intense physical exertion is crucial for athlete well-being and performance.
Purpose of the Study:
- To investigate the effects of Saengmaeksan (SMS) supplementation on fatigue markers, liver function enzymes, and immunoglobulin levels in college tennis players undergoing high-intensity training.
- To test the hypothesis that SMS intake can ameliorate the negative physiological impacts of strenuous exercise on fatigue, liver health, and immune status.
Main Methods:
- Seventeen male college tennis players participated in a 4-week high-intensity training program (70%-90% heart rate reserve, 5 times/week).
- Participants were randomized into two groups: one receiving 110 mL of SMS daily (total 770 mL) and a placebo group.
- Measurements included ammonia, lactic acid, aspartate transaminase (AST), alanine aminotransferase (ALT), and immunoglobulin (IgA, IgG, IgM) levels.
Main Results:
- Significant interaction effects were observed for ammonia, ALT, and IgA between the SMS and control groups.
- SMS intake led to a significant decrease in ammonia, AST, and ALT levels, indicating reduced fatigue and improved liver function.
- IgA levels significantly increased with SMS consumption, while IgM levels decreased in both groups; IgG levels showed no significant change.
Conclusions:
- Saengmaeksan (SMS) supplementation appears effective in reducing markers of fatigue (ammonia) and improving liver function (AST, ALT) in athletes engaged in high-intensity training.
- SMS intake positively influences the immune system by increasing IgA levels, suggesting a potential role in supporting immune function during intense physical stress.
- These findings suggest that SMS may be a beneficial adjunct for athletes to manage physiological stress associated with high-intensity training.
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