Related Experiment Video
Updated: Jul 24, 2025

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
Published on: June 8, 2022
The Great Imitator Strikes Again: A Case of a Lupus Flare-up Presenting Like an Acute Abdomen
Emmanouil Kiriakopoulos1,2, Vanessa Perez3, Robyn Hoelle1,2
1North Florida Regional Medical Center, Department of Graduate Medical Education.
Abstract:
Description Systemic lupus erythematosus (SLE) is an autoimmune disease affecting all age groups and can manifest in various forms, often making the initial or successive presentations difficult to diagnose. Peritonitis secondary to lupus is a rare manifestation of this disease and the prevalence is said to be much lower in children. We present a case report of an adolescent male with a known history of lupus who presented to the emergency department with a clinical picture consistent with an acute surgical abdomen and underwent an appendectomy. Subsequent workup identified the culprit as a lupus-related peritonitis requiring corticosteroids for resolution.
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