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Antineutrophil Cytoplasmic Antibody (ANCA)-Associated Aortitis Presenting With Acute Dissection: Case Report and

Obteene Azimi-Ghomi1, Jorge De La Portilla1

  • 1Department of General and Vascular Surgery, HCA Florida Kendall Hospital, Miami, FL.

HCA Healthcare Journal of Medicine
|July 10, 2023
PubMed

Insights

This study details a rare case of ANCA-associated aortitis, a condition affecting large blood vessels, complicated by acute iliac artery dissection. Successful management involved corticosteroids and endovascular stenting.

Area of Science:

  • Vascular Medicine
  • Rheumatology
  • Immunology

Background:

  • Vasculitides encompass inflammatory diseases of blood vessel walls, classified by vessel size (large, medium, small).
  • ANCA-associated vasculitis (AAV) typically affects small vessels, but large vessel involvement, such as aortitis, is occasionally reported.
  • ANCA-associated aortitis is a rare condition with limited diagnostic and treatment evidence.

Observation:

  • An 80-year-old male presented with ANCA-associated aortitis.
  • The patient experienced a complication of acute dissection of the left common iliac artery.
  • This presentation represents a potentially novel association of ANCA-associated aortitis with acute dissection.

Findings:

  • The case was successfully managed using corticosteroid therapy.
  • Endovascular stenting was employed to treat the involved iliac artery.
  • This approach highlights a viable treatment strategy for this rare vascular complication.

Implications:

  • This case expands the understanding of ANCA-associated aortitis presentations.
  • It underscores the importance of considering AAV in large vessel pathologies.
  • The successful management provides insights for future clinical practice in rare vasculitic diseases.

Keywords:
agedantineutrophil cytoplasmic antibodyaortic diseasesaortitisautoimmune diseasescANCAdissecting aneurysmvasculitis

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