Status of genome function annotation in model organisms and crops

Area of Science:

• Genomics
• Bioinformatics
• Computational Biology

Background:

• Significant advancements in genome-enabled biology have occurred over decades.
• Accessing and disseminating gene function information remains challenging for many scientists and genomes.
• A gap exists in easily accessible, graphical summaries of genome function annotation status.

Purpose of the Study:

• To create a web application for visualizing, searching, and downloading genome annotation data.
• To provide easy access to genome function annotation status for 28 species, including model organisms and crop species.
• To address the grand challenge of elucidating all gene functions in organisms.

Main Methods:

• Developed a web application (https://genomeannotation.rheelab.org) for data visualization and access.
• Included functionality to search and download genome annotation data.
• Established semi-annual updates and archival of data snapshots for a historical record.

Main Results:

• A web application is now available for accessing genome annotation data.
• The application provides graphical summaries and data tables for 28 species.
• The tool visualizes the current status of genome function annotation, highlighting unknown functions.

Conclusions:

• The web application offers a clear and simple visualization of genome function annotation status.
• Regular updates and archiving ensure access to current and historical data.
• This resource will aid scientists in understanding gene functions and advancing genomic research.