Ewing's sarcoma arising from the right sided chest wall: a case report

Area of Science:

• Oncology
• Thoracic Surgery
• Skeletal System Neoplasms

Background:

• Ewing sarcoma (ES) is a prevalent malignancy in young adults, often diagnosed late with significant chest wall involvement.
• Current 5-year survival rates for ES range between 40-60%, indicating a need for effective treatment strategies.
• Patients frequently present with symptoms like chest pain and respiratory distress due to large tumor masses.

Purpose of the Study:

• To present a case of a 21-year-old female diagnosed with right-sided chest wall Ewing sarcoma.
• To detail the treatment approach involving neoadjuvant chemotherapy and surgical resection.
• To evaluate the efficacy and tolerability of chest wall reconstruction following tumor removal.

Main Methods:

• Diagnosis was confirmed via fine needle aspiration cytology.
• The patient received neoadjuvant chemotherapy.
• Maximal safe tumor resection was performed, followed by chest wall reconstruction using double prolene mesh and bone cement, with defect closure using adjacent ribs.

Main Results:

• The surgical intervention resulted in complete tumor resection.
• Postoperative recovery was favorable, with significant resolution of presenting symptoms.
• The chest wall reconstruction procedure was well-tolerated and effective.

Conclusions:

• Surgical resection combined with chest wall reconstruction is an effective treatment for chest wall Ewing sarcoma.
• This approach offers a good prognosis and symptom relief for affected patients.
• The described reconstruction technique is a viable and well-tolerated option for managing chest wall defects.