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Mad honey poisoning presenting with syncopal attack: a case report.

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Mad honey poisoning, caused by grayanotoxins, can lead to serious symptoms like bradycardia and hypotension. While usually mild, severe complications necessitate prompt medical attention and monitoring.

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Area of Science:

  • Toxicology
  • Pharmacology
  • Cardiology

Background:

  • Mad honey, derived from Rhododendron nectar, contains grayanotoxins.
  • Traditionally used in the Himalayas for purported medicinal benefits.
  • Grayanotoxins are known to cause poisoning through Rhododendron consumption.

Purpose of the Study:

  • To present a case of mad honey poisoning.
  • To highlight the clinical presentation and management of grayanotoxin intoxication.
  • To discuss potential life-threatening complications of mad honey consumption.

Main Methods:

  • Case report of a 62-year-old male with mad honey poisoning.
  • Emergency department presentation with loss of consciousness, bradycardia, and hypotension.
  • Treatment included intravenous fluids, atropine, vasopressor support, and coronary care unit monitoring.

Main Results:

  • The patient experienced severe symptoms including loss of consciousness, bradycardia, and hypotension.
  • Grayanotoxins I and II are identified as the primary toxins responsible for intoxication.
  • Common symptoms include hypotension, dizziness, nausea, vomiting, and impaired consciousness.

Conclusions:

  • Mad honey intoxication typically requires symptomatic treatment and close observation.
  • Life-threatening complications such as cardiac asystole, convulsions, and myocardial infarction can occur.
  • Awareness of potential severe outcomes is crucial for managing mad honey poisoning.