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Updated: Jul 24, 2025

Sterile Pericarditis in Aachener Minipigs As a Model for Atrial Myopathy and Atrial Fibrillation
Published on: September 24, 2021
Gut Microbiota and Atrial Fibrillation: Pathogenesis, Mechanisms and Therapies
Ahmed M Al-Kaisey1,2, William Figgett3, Joshua Hawson1,2
1Department of Cardiology, Royal Melbourne Hospital, Melbourne, Australia.
Abstract:
Over the past decade there has been an interest in understanding the role of gut microbiota in the pathogenesis of AF. A number of studies have linked the gut microbiota to the occurrence of traditional AF risk factors such as hypertension and obesity. However, it remains unclear whether gut dysbiosis has a direct effect on arrhythmogenesis in AF. This article describes the current understanding of the effect of gut dysbiosis and associated metabolites on AF. In addition, current therapeutic strategies and future directions are discussed.
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