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Psychosocial factors impacting antegrade continence enema outcomes in pediatric patients
Kari Benson1,2, Ashley Bazier1, Katherine Schwartzkopf1
1Indiana University School of Medicine, Indianapolis, Indiana, USA.
Insights
Psychosocial factors impact outcomes for children undergoing antegrade continence enema (ACE) procedures for constipation. Further research is needed to develop guidelines for pre-procedure evaluations to improve treatment success.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Child Psychology
Background:
- Constipation and encopresis in children often require medication and behavioral therapies.
- Antegrade continence enema (ACE) procedures are surgical options for persistent constipation.
- While many children benefit from ACE, some experience ongoing incontinence, complications, or stoma issues.
Purpose of the Study:
- To review existing research on psychosocial factors influencing ACE treatment outcomes and complications.
- To identify knowledge gaps and support future research for developing pre-procedure evaluation guidelines.
- To inform ACE candidacy and interventions for high-risk children.
Main Methods:
- Literature review of studies examining psychosocial factors and ACE outcomes.
- Analysis of identified factors such as age, psychiatric symptoms, and adherence.
- Synthesis of current evidence and limitations in research.
Main Results:
- Psychosocial factors are implicated in ACE treatment success and complications.
- Limited research currently exists on the specific impact of these factors.
- Age, psychiatric symptoms, and adherence to the ACE regimen are noted as potential influences.
Conclusions:
- Standardized biopsychosocial guidelines for ACE candidacy are currently lacking.
- Pre-procedure psychosocial evaluations could enhance patient selection and post-operative care.
- Further investigation is crucial to establish evidence-based guidelines for optimizing ACE outcomes.
Background:
Children with constipation and encopresis are often treated with medication and behavioral approaches. When constipation persists, surgical interventions such as antegrade continence enema (ACE) procedures are considered. Many children benefit from these procedures; however, some children continue to have incontinence, experience complications, or discontinue the use of the ACE stoma. There is some evidence in the literature to indicate that psychosocial factors can have an impact on ACE outcomes; however, standardized biopsychosocial guidelines related to ACE candidacy and surgery do not currently exist.
Purpose:
The purpose of this review is to summarize the research to date on psychosocial factors related to ACE treatment outcomes and complications. Identifying what is known and what limitations remain can support future research to inform development of guidelines for pre-procedure evaluations. Psychosocial pre-procedure evaluations could help to inform eligibility for the procedure as well as interventions to enhance outcomes for children at increased risk for poor outcomes or complications from ACE. Age, psychiatric symptoms, and adherence to the ACE flush regimen were some of the factors identified in the literature as impacting ACE outcomes; however, there is limited research in this area.
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