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Updated: Jul 24, 2025

Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model
Published on: May 26, 2023
Cardiac surgery simulation: step-by-step Nicks procedure in a preclinical model.
Francesca Toto1, Tiziano Torre2, Alberto Pozzoli3
1Istituto Cardiocentro Ticino, Lugano, Switzerland.
The Nicks operation, a posterior aortic root enlargement technique, was successfully demonstrated on a preclinical porcine heart model. This procedure aids in implanting appropriately sized prosthetic aortic valves by enlarging the aortic annulus.
Area of Science:
- Cardiovascular Surgery
- Surgical Innovation
- Preclinical Research
Background:
- The Nicks operation is a posterior aortic root enlargement procedure.
- Its primary goal is to enable the implantation of a correctly sized aortic prosthetic valve.
- This technique is crucial for complex aortic valve replacement cases.
Discussion:
- The procedure involves a longitudinal incision in the non-coronary sinus of the aortic root.
- Care is taken to avoid the fibrous body between the aortic valve and mitral valve.
- A patch is inserted to augment the aortic annulus, increasing its diameter.
Key Insights:
- Successful demonstration of the Nicks operation on a porcine heart model.
- Validation of the surgical technique for aortic annulus enlargement.
- Potential to improve outcomes in aortic valve replacement surgery.
Outlook:
- Further preclinical studies may refine the Nicks operation technique.
- Potential for clinical translation in patients requiring aortic root enlargement.
- Advancement in surgical options for aortic valve prostheses implantation.
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