MANAGEMENT OF ATRIAL FIBRILLATION, VENTRICULAR ARRHYTHMIA, LEFT VENTRICULAR DYSFUNCTION, AND SUBSEQUENT CARDIOPATHOLOGIC EVALUATION IN AN ORANGUTAN (PONGO PYGMAEUS × ABELII)
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Updated: Jul 24, 2025

Sterile Pericarditis in Aachener Minipigs As a Model for Atrial Myopathy and Atrial Fibrillation
Published on: September 24, 2021
Kathryn S Leach1, Sam Rivera2, William Devlin3
1Zoo Atlanta, Atlanta, GA 30315, USA, kleach@zooatlanta.org.
Insights
This case study details the successful diagnosis and management of heart disease in an orangutan, highlighting the importance of cardiac screening and comprehensive evaluation in apes.
Area of Science:
- Veterinary Cardiology
- Primate Medicine
- Comparative Pathology
Background:
- Preventative health examinations are crucial for early detection of diseases in non-human primates.
- Orangutans, like other great apes, can develop cardiovascular conditions similar to humans.
- Vasectomized male orangutans may require specific health monitoring protocols.
Purpose of the Study:
- To report the successful diagnosis and medical management of left ventricular dysfunction and arrhythmias in a hybrid orangutan.
- To emphasize the significance of regular cardiac screening and diagnostic procedures in orangutan healthcare.
- To illustrate the value of integrated antemortem and postmortem cardiac evaluations.
Main Methods:
- Diagnosis involved physical examination, echocardiography, and electrocardiography (ECG).
- Treatment included carvedilol, amiodarone, furosemide, spironolactone, clopidogrel, and aspirin.
- Comprehensive necropsy was performed following the animal's death.
Main Results:
- The orangutan was diagnosed with left ventricular dysfunction, atrial fibrillation, and ventricular arrhythmia.
- Medical management led to improved activity levels, restoration of sinus rhythm, and enhanced left ventricular function.
- The animal survived for 27 months post-diagnosis.
Conclusions:
- Early detection and multi-faceted treatment strategies can effectively manage complex cardiac conditions in orangutans.
- Behavioral training and cardiac screening are vital components of preventative care for apes.
- Thorough postmortem examination complements clinical findings and aids in understanding disease progression.
Abstract:
A 37-yr-old male vasectomized hybrid orangutan (Pongo pygmaeus × abelii) was diagnosed with left ventricular dysfunction during a preventative health care examination. Treatment was initiated with carvedilol. The following year, this orangutan was evaluated for intermittent lethargy. Following observation of an irregular cardiac rhythm during an echocardiogram, a lead II electrocardiogram revealed atrial fibrillation and ventricular arrhythmia. Additional treatment included amiodarone, furosemide, spironolactone, clopidogrel, and aspirin. An improved activity level was noted, and follow-up testing showed restoration of a sinus rhythm, reduced frequency of ventricular arrhythmia, and improved left ventricular function. The orangutan died 27 mon after initial diagnosis of heart disease, and a complete necropsy was performed. This article describes successful diagnosis and management of structural and arrhythmic heart disease in an orangutan, emphasizing the role of cardiac disease screening and behavioral training in apes, as well as the value of matching thorough antemortem and postmortem cardiac evaluation.
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