Jove
Visualize
Contact Us

Related Concept Videos

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

148
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
148

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Chronological ageing and ovarian reserve in MS: insights from anti-Müllerian hormone and disability progression.

Journal of neurology, neurosurgery, and psychiatry·2026
Same author

Dihydroartemisinin for the treatment of polycystic ovary syndrome: study protocol for a multi-centre placebo-controlled randomised clinical trial.

BMJ open·2026
Same author

Reply: Reconsidering the interpretation of sperm DNA fragmentation testing in ART decision-making.

Human reproduction open·2026
Same author

Prognostic value of cervical length for spontaneous preterm birth in asymptomatic women with singleton pregnancy: An individual participant data meta-analysis.

PLoS medicine·2026
Same author

Randomised, triple-blind, placebo-controlled trial of atosiban in women with previous embryo implantation failure and abnormal uterine contractions undergoing single blastocyst-stage embryo transfer: a study protocol.

BMJ open·2026
Same author

Spontaneous Preterm Birth and Subsequent Cardiovascular Mortality: Linked Registry Cohort Study.

BJOG : an international journal of obstetrics and gynaecology·2026
Same journal

WIC Participation and the Education-Related Gap in Adverse Neonatal Outcomes: A Population-Based Cohort Study.

American journal of perinatology·2026
Same journal

Low-Dose Aspirin Prophylaxis for Preeclampsia and the Risk of Postpartum Hypertensive Outcomes: A Propensity Score Analysis.

American journal of perinatology·2026
Same journal

Cystic periventricular leukomalacia in preterm infants: Clinical risks and heart rate and oxygenation patterns.

American journal of perinatology·2026
Same journal

International consensus curriculum and competency framework for maternal point-of-care ultrasound training.

American journal of perinatology·2026
Same journal

From InSurE to MIST: A Quality Improvement Initiative in a Level IV NICU.

American journal of perinatology·2026
Same journal

Adverse Perinatal Outcomes by Gestational Surrogacy Status among In Vitro Fertilization Pregnancies.

American journal of perinatology·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 24, 2025

Author Spotlight: Advancing Pelvic Prolapse Treatment with a Non-Mesh Approach using Laparoscopic Pectopexy
03:30

Author Spotlight: Advancing Pelvic Prolapse Treatment with a Non-Mesh Approach using Laparoscopic Pectopexy

Published on: October 25, 2024

1.5K

PROMPT: Prospective Meta-analysis for Pessary Trials Study Protocol.

Elizabeth A Thom1, George R Saade2, Lisa M Askie3

  • 1The George Washington University Biostatistics Center, Washington, District of Columbia.

American Journal of Perinatology
|July 10, 2023
PubMed
Summary
This summary is machine-generated.

A short cervix is a strong predictor of preterm birth. An international collaboration formed the PROspective Meta-analysis of Pessary Trials (PROMPT) to analyze data from randomized trials of cervical pessary use to prevent preterm birth.

More Related Videos

Laparoscopic Non-Mesh Cerclage Pectopexy for Pelvic Organ Prolapse
03:43

Laparoscopic Non-Mesh Cerclage Pectopexy for Pelvic Organ Prolapse

Published on: September 13, 2022

5.5K
E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
06:28

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy

Published on: August 1, 2019

8.4K

Related Experiment Videos

Last Updated: Jul 24, 2025

Author Spotlight: Advancing Pelvic Prolapse Treatment with a Non-Mesh Approach using Laparoscopic Pectopexy
03:30

Author Spotlight: Advancing Pelvic Prolapse Treatment with a Non-Mesh Approach using Laparoscopic Pectopexy

Published on: October 25, 2024

1.5K
Laparoscopic Non-Mesh Cerclage Pectopexy for Pelvic Organ Prolapse
03:43

Laparoscopic Non-Mesh Cerclage Pectopexy for Pelvic Organ Prolapse

Published on: September 13, 2022

5.5K
E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
06:28

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy

Published on: August 1, 2019

8.4K

Area of Science:

  • Maternal-fetal medicine
  • Perinatology
  • Obstetrics

Background:

  • Preterm birth (<37 weeks gestation) is a major cause of infant mortality and long-term disability.
  • A short cervix in the second trimester is a significant predictor of spontaneous preterm birth.
  • Previous studies on the effectiveness of Arabin pessary for preventing preterm birth in singleton gestations with short cervix have yielded conflicting results.

Purpose of the Study:

  • To establish an international collaborative of randomized trials investigating the use of pessary for singleton and twin gestations with a short cervix.
  • To conduct a prospective individual patient data (IPD) meta-analysis of these trials.

Main Methods:

  • Formation of the PROspective Meta-analysis of Pessary Trials (PROMPT) collaboration in November 2014.
  • Agreement on IPD meta-analysis hypotheses, eligibility criteria, and core outcome measures for singleton and twin gestations.
  • Primary outcome: composite of fetal death or preterm delivery before 32 weeks' gestation; secondary outcomes include maternal and neonatal morbidities.

Main Results:

  • Results are to be published in phases as individual studies conclude.
  • The first phase of results from singleton and twin pessary trials is anticipated in late 2022.
  • Updates will be provided as participating trials are completed and published.

Conclusions:

  • A meta-analysis of pessary trials is underway to clarify its efficacy in preventing preterm birth.
  • Short cervical length is a validated predictor of preterm birth.
  • Further results from the PROMPT collaboration will inform clinical practice regarding cervical support.