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Related Experiment Videos

Photocontact urticaria from chlorpromazine.

C R Lovell, E Cronin, E L Rhodes

    Contact Dermatitis
    |May 1, 1986
    PubMed
    Summary

    Chlorpromazine commonly causes delayed photosensitive eczema. This case highlights typical symptoms, including urticarial lesions identified through photopatch testing.

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    Area of Science:

    • Dermatology
    • Photodermatology
    • Clinical Medicine

    Background:

    • Chlorpromazine is a phenothiazine antipsychotic medication.
    • Photosensitive eczema is a known adverse reaction to certain drugs.
    • Delayed onset of photosensitivity can complicate diagnosis.

    Observation:

    • A patient presented with clinical features characteristic of drug-induced photosensitive eczema.
    • The patient's reaction was linked to chlorpromazine use.
    • Specific diagnostic testing was performed.

    Findings:

    • The patient exhibited typical delayed photosensitive eczema symptoms.
    • Photopatch testing confirmed chlorpromazine as the causative agent.
    • Urticarial lesions were also observed upon photopatch testing.

    Implications:

    • This case reinforces chlorpromazine's role in photosensitive eczema.
    • Photopatch testing is crucial for identifying drug-induced photosensitivity.
    • Awareness of this adverse effect is important for clinicians managing patients on chlorpromazine.

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