Jove
Visualize
Contact Us

Related Concept Videos

Reaction Mechanisms03:06

Reaction Mechanisms

26.0K
Chemical reactions often occur in a stepwise fashion, involving two or more distinct reactions taking place in a sequence. A balanced equation indicates the reacting species and the product species, but it reveals no details about how the reaction occurs at the molecular level. The reaction mechanism (or reaction path) provides details regarding the precise, step-by-step process by which a reaction occurs.
For instance, the decomposition of ozone appears to follow a mechanism with two steps:
26.0K
Multi-Step Reactions02:31

Multi-Step Reactions

7.4K
Chemical reactions often occur in a stepwise fashion involving two or more distinct reactions taking place in a sequence. A balanced equation indicates the reacting species and the product species, but it reveals no details about how the reaction occurs at the molecular level. The reaction mechanism (or reaction path) provides details regarding the precise, step-by-step process by which a reaction occurs. Each of the steps in a reaction mechanism is called an elementary reaction. These...
7.4K
Synthesis and Decomposition Reactions02:17

Synthesis and Decomposition Reactions

33.0K
Synthesis and decomposition are two types of redox reactions. Synthesis means to make something, whereas decomposition means to break something. The reactions are accompanied by chemical and energy changes. 
33.0K
Step-Growth Polymerization: Overview01:03

Step-Growth Polymerization: Overview

3.5K
Step-growth or condensation polymerization is a stepwise reaction of bi or multifunctional monomers to form long-chain polymers. As all the monomers are reactive, most of the monomers are consumed at the early stages of the reaction to form small chains of reactive oligomers, which then combine to form long polymer chains in the late stages. Hence, the reaction has to proceed for a long time to achieve high molecular weight polymers.
Many natural and synthetic polymers are produced by...
3.5K
Olefin Metathesis Polymerization: Overview01:13

Olefin Metathesis Polymerization: Overview

2.2K
Recently, the development of olefin metathesis polymerization advanced the field of polymer synthesis. Simply put, the reorganization of substituents on their double bonds between two olefins in the presence of a catalyst is known as the olefin metathesis reaction. The use of metathesis reaction for polymer synthesis is called olefin metathesis polymerization.
Ruthenium-based Grubbs catalyst is the most commonly used catalyst for olefin metathesis polymerization. Grubbs catalyst consists...
2.2K
ATP and Macromolecule Synthesis01:28

ATP and Macromolecule Synthesis

5.6K
Biological macromolecules are organic compounds, predominantly composed of carbon atoms. The carbon atoms are covalently bonded with hydrogen, oxygen, nitrogen, and other minor elements. There are four major biological macromolecule classes: carbohydrates, lipids, proteins, and nucleic acids.
Most macromolecules are composed of single subunits, or building blocks, called monomers. The monomers combine with each other using covalent bonds to form larger molecules known as polymers.
Conversion of...
5.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quenching Single-Fluorophore Systems and the Emergence of Nonlinear Stern-Volmer Plots.

ACS omega·2026
Same author

Modeling and Elucidating the Behavior of a Thermoresponsive LCST Ionic Liquid.

Journal of chemical information and modeling·2025
Same author

Breakdown of Langmuir Adsorption Isotherm in Small Closed Systems.

Langmuir : the ACS journal of surfaces and colloids·2024
Same author

Statistical mechanics of dimerizations and its consequences for small systems.

Physical chemistry chemical physics : PCCP·2022
Same author

Binding reactions at finite systems.

Physical chemistry chemical physics : PCCP·2022
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 24, 2025

Optimization of Radiochemical Reactions using Droplet Arrays
10:54

Optimization of Radiochemical Reactions using Droplet Arrays

Published on: February 12, 2021

3.5K

Multimerizations, Aggregation, and Transfer Reactions of Small Numbers of Molecules.

Ronen Zangi1,2,3

  • 1Donostia International Physics Center (DIPC), 20018 Donostia-San Sebastián, Spain.

Journal of Chemical Information and Modeling
|July 11, 2023
PubMed
Summary

This study introduces a new equilibrium constant expression accounting for reactant concentration cross-correlations in multimerization. This approach ensures a constant value across various conditions, unlike traditional methods that show significant variations.

More Related Videos

Optimization of the Ugi Reaction Using Parallel Synthesis and Automated Liquid Handling
08:24

Optimization of the Ugi Reaction Using Parallel Synthesis and Automated Liquid Handling

Published on: November 11, 2008

16.4K
Ethylene Polymerizations Using Parallel Pressure Reactors and a Kinetic Analysis of Chain Transfer Polymerization
07:28

Ethylene Polymerizations Using Parallel Pressure Reactors and a Kinetic Analysis of Chain Transfer Polymerization

Published on: November 27, 2015

13.3K

Related Experiment Videos

Last Updated: Jul 24, 2025

Optimization of Radiochemical Reactions using Droplet Arrays
10:54

Optimization of Radiochemical Reactions using Droplet Arrays

Published on: February 12, 2021

3.5K
Optimization of the Ugi Reaction Using Parallel Synthesis and Automated Liquid Handling
08:24

Optimization of the Ugi Reaction Using Parallel Synthesis and Automated Liquid Handling

Published on: November 11, 2008

16.4K
Ethylene Polymerizations Using Parallel Pressure Reactors and a Kinetic Analysis of Chain Transfer Polymerization
07:28

Ethylene Polymerizations Using Parallel Pressure Reactors and a Kinetic Analysis of Chain Transfer Polymerization

Published on: November 27, 2015

13.3K

Area of Science:

  • Physical Chemistry
  • Chemical Physics
  • Thermodynamics

Background:

  • Macroscopic chemical equilibria differ from small-particle systems.
  • Traditional equilibrium constant expressions neglect reactant concentration correlations.

Purpose of the Study:

  • To develop and validate a new equilibrium constant expression for multimerization that includes cross-correlations.
  • To demonstrate the constancy of this new expression across different conditions and system sizes.

Main Methods:

  • Application of a recently proposed equilibrium constant expression for binding.
  • Formulation of equilibrium constants for cluster formation (trimer, tetramer, pentamer) via series of two-body reactions.
  • Molecular dynamics simulations to test the expression's validity.

Main Results:

  • The new expression, including cross-correlations, yields a constant equilibrium constant value.
  • Traditional expressions ignoring correlations show large variations (orders of magnitude).
  • The derived relation between average particle number and fluctuations holds even with coupled reactions.

Conclusions:

  • Cross-correlations are essential for accurate equilibrium constant expressions in multimerization.
  • The new expression provides a robust and consistent description of chemical equilibria.
  • Molecular dynamics simulations validate the theoretical framework for small systems.