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How Should We Approach Body Size Diversity in Clinical Trials?
Dania Pagarkar1, Erin Harrop2, Lisa Erlanger3
1Fourth-year medical student at the University of Southern California Keck School of Medicine in Los Angeles.
Abstract:
Regulatory and ethical considerations mandate that minorities affected by health disparities be included in research. Despite concerns about clinical outcomes for patients with obesity, clinical trials have reported few data about participation of and outcomes for such patients. This article examines the lack of body size diversity in clinical research participants and reviews the evidence and ethical arguments for including larger-bodied patients. Drawing on examples of improved gender diversification of trial participants, this article suggests that similar benefits would be likely from inclusion of body diversity.
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