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Updated: Jul 23, 2025

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
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Clinical Presentation and Prognosis.

Christopher P Millward1,2, Sumirat Keshwara1,2, Abdurrahman I Islim1,2

  • 1Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.

Advances in Experimental Medicine and Biology
|July 11, 2023
PubMed
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Advances in understanding meningioma biology and management have improved patient outcomes. Research now focuses on molecular factors and patient-centered quality of life measures for personalized meningioma care.

Keywords:
Clinical trialIncidentalMeningiomaRadiotherapySurgery

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Area of Science:

  • Neuro-oncology
  • Neurosurgery
  • Molecular Biology

Background:

  • Meningioma care has advanced significantly over 30 years.
  • Improved understanding of tumor biology, classification, and management strategies.
  • Increased focus on patient-centered outcomes and quality of life.

Purpose of the Study:

  • To review clinical presentations of meningioma, including incidental findings.
  • To examine prognostic factors (clinical, pathological, molecular).
  • To discuss the evolving landscape of meningioma research and personalized treatment.

Main Methods:

  • Review of clinical presentations and natural history.
  • Analysis of prognostic indicators.
  • Discussion of molecular and genomic factors.

Main Results:

  • Improved clinical outcomes and prognosis for meningioma patients.
  • Identification of molecular factors for personalized management.
  • Growing interest in patient-reported quality of life.

Conclusions:

  • Meningioma management has progressed through enhanced biological understanding and treatment options.
  • Prognostic factors are crucial for predicting outcomes.
  • Future strategies emphasize personalized medicine and patient well-being.