Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

MoS<sub>2</sub>-loaded cholesteric liquid crystal microcapsules for NIR responsive thermochromism.

Lab on a chip·2026
Same author

Insights into the conversion of odor compounds by a novel microbial agent during swine manure storage: a multi-omics integration of microbiome, metabolome and genome.

Waste management (New York, N.Y.)·2026
Same author

Temporal response patterns of swine gut microbiota to arabinoxylan.

Journal of advanced research·2026
Same author

Sex-Related Differences in Maximum Bite Force, Occlusal Contact Area and Bite Pressure in Healthy Young Asian Adults.

Journal of oral rehabilitation·2026
Same author

Decoupling-Facilitated Mass-Charge Transfer via Dual-Interface Engineering for Efficient CO<sub>2</sub> Electrolysis.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Nomogram prediction of acute kidney injury following modified Morrow myectomy in hypertrophic obstructive cardiomyopathy: insights from 12 years of outcomes.

BMC cardiovascular disorders·2026

Related Experiment Video

Updated: Jul 23, 2025

Electrowetting-based Digital Microfluidics Platform for Automated Enzyme-linked Immunosorbent Assay
08:22

Electrowetting-based Digital Microfluidics Platform for Automated Enzyme-linked Immunosorbent Assay

Published on: February 23, 2020

9.6K

Replaceable Dielectric Film for Low-Voltage and High-Performance Electrowetting-Based Digital Microfluidics.

Jieping Cao1,2, Xiaodong Zeng1, Shitao Shen2

  • 1Guangdong Provincial Key Laboratory of Nanophotonic Functional Materials and Devices, School of Information and Optoelectronic Science and Engineering, South China Normal University, Guangzhou 510006, P. R. China.

Langmuir : the ACS Journal of Surfaces and Colloids
|July 11, 2023
PubMed
Summary

A novel polymer-ion gel-amorphous fluoropolymer (PIGAF) dielectric layer enhances electrowetting-on-dielectric (EWOD) devices for digital microfluidics (DMF). This PIGAF layer enables stable, low-voltage droplet manipulation for chemical reactions and biomedical sensing.

More Related Videos

Taking Advantage of Reduced Droplet-surface Interaction to Optimize Transport of Bioanalytes in Digital Microfluidics
07:57

Taking Advantage of Reduced Droplet-surface Interaction to Optimize Transport of Bioanalytes in Digital Microfluidics

Published on: November 10, 2014

7.9K
Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation
13:42

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Published on: September 19, 2017

11.8K

Related Experiment Videos

Last Updated: Jul 23, 2025

Electrowetting-based Digital Microfluidics Platform for Automated Enzyme-linked Immunosorbent Assay
08:22

Electrowetting-based Digital Microfluidics Platform for Automated Enzyme-linked Immunosorbent Assay

Published on: February 23, 2020

9.6K
Taking Advantage of Reduced Droplet-surface Interaction to Optimize Transport of Bioanalytes in Digital Microfluidics
07:57

Taking Advantage of Reduced Droplet-surface Interaction to Optimize Transport of Bioanalytes in Digital Microfluidics

Published on: November 10, 2014

7.9K
Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation
13:42

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Published on: September 19, 2017

11.8K

Area of Science:

  • Materials Science
  • Microfluidics
  • Surface Science

Background:

  • Electrowetting-on-dielectric (EWOD) is crucial for digital microfluidic (DMF) applications, with the dielectric layer's properties dictating device performance.
  • Existing dielectric layers face challenges in balancing driving voltage, reliability, and device lifetime.

Purpose of the Study:

  • To develop a novel composite film for EWOD devices that offers high efficiency, stability, and low-voltage operation.
  • To investigate the potential of ion gel (IG)-based materials for advanced hydrophobic dielectric layers.

Main Methods:

  • Fabrication of a polymer (P)-ion gel-amorphous fluoropolymer (PIGAF) composite film.
  • Integration of the PIGAF film as a dielectric layer in EWOD-DMF devices.
  • Characterization of droplet contact angle changes, hysteresis, actuation voltage, and droplet motion velocity.

Main Results:

  • The PIGAF dielectric layer enabled EWOD devices to achieve a large contact angle change (∼50°) with low hysteresis (≤5°) at 30 Vrms.
  • Actuation voltage remained stable across varying PIGAF film thicknesses (several to tens of microns).
  • Stable droplet actuation was demonstrated at 30 Vrms, with a maximum velocity of 69 mm/s at 140 Vrms, and maintained performance over ≥50 cycles and 1 year of storage.

Conclusions:

  • The PIGAF composite film is a promising, stable, and reliable dielectric material for high-efficiency EWOD-DMF devices.
  • The developed EWOD-DMF system is suitable for applications in digital chemical reactions and biomedical sensing.
  • The thickness-independent actuation voltage offers design flexibility for microfluidic devices.