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Updated: Jul 23, 2025

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
Published on: December 21, 2019
Occult breast cancer with pleural metastasis
Roya Faghani1, Sahar Darabi Monadi2
1University Hospital North Midland, The Breast Centre, Royal Stoke University Hospital, Stoke On Trent, Staffordshire, UK.
Abstract:
Carcinoma of unknown primary (CUP) is defined as histologically confirmed metastases from an undetectable malignant primary site. A subgroup of CUP, known as occult breast cancer (OBC), is a biopsy-proven metastatic breast cancer without an original breast tumor. It remains a diagnostic and therapeutic enigma as there is no consensus on the diagnostic and treatment approaches for the patients with OBC. This case report is a unique presentation of OBC, emphasizing the importance of identifying OBC patients in the early stages. A dedicated team of experts and a more definitive approach to diagnosis and treatment of OBC are essential to prevent delays in the whole process.
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