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Correlation between thyroid function indices and urine iodine levels in patients with nodular goiter
Shifa Yuan1, Caixia Liu1, Zhijun Liu1
1Hospital of Hebei Province Crop of Chinese People's Armed Police Force Shijiazhuang 050081, Hebei, China.
American Journal of Translational Research
|July 12, 2023
Summary
Urinary iodine levels were higher in patients with nodular goiter (NG) compared to healthy individuals. Monitoring iodine status is crucial for managing thyroid function in NG patients.
Area of Science:
- Endocrinology
- Nutritional Science
- Thyroidology
Background:
- Nodular goiter (NG) is a common thyroid condition.
- Iodine intake significantly impacts thyroid function and health.
- Understanding iodine status in NG patients is essential for management.
Purpose of the Study:
- To assess iodine nutritional status in patients with nodular goiter.
- To investigate the relationship between urinary iodine levels and thyroid function indices in NG patients.
Main Methods:
- Retrospective analysis of 173 nodular goiter patients and 172 healthy controls.
- Comparison of urinary iodine levels between groups.
- Correlation analysis between urinary iodine and thyroid hormones (TSH, FT3, FT4) in NG patients.
Main Results:
- Nodular goiter patients exhibited higher urinary iodine levels than controls (P < 0.05).
- Higher iodine excess rates were observed in females compared to males.
- Urinary iodine negatively correlated with TSH and positively with FT3 and FT4 in hyperthyroid NG patients.
Conclusions:
- A significant association exists between urinary iodine levels and thyroid hormone levels in nodular goiter patients.
- Regular monitoring of urinary iodine is vital for appropriate iodine supplementation in NG management.
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