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Transpyloric Feed in Reflux-Associated Apnea in Preterm Newborns: A Prospective Study
Tamoghna Biswas1, Tapas K Sabui1, Somosri Roy1
1Medical College, Calcutta, India.
HCA Healthcare Journal of Medicine
|July 12, 2023
Summary
Transpyloric feeding significantly reduced apnea in preterm infants with gastroesophageal reflux. This intervention offers a potential therapeutic option for reflux-associated apnea in neonates.
Area of Science:
- Neonatal Medicine
- Pediatric Gastroenterology
- Clinical Research
Background:
- The link between gastroesophageal reflux (GER) and apnea in neonates is debated.
- This study investigates the etiological correlation between GER and apnea.
Purpose of the Study:
- To evaluate the efficacy of transpyloric feeding in reducing apneic episodes in preterm neonates with GER-associated apnea.
- To assess the safety and impact of continuous transpyloric tube feeding.
Main Methods:
- A prospective interventional study was conducted on preterm neonates with apnea and GER features.
- Participants received continuous transpyloric tube feeding for 72 hours.
- Apneic episodes were counted before and after initiating nasoduodenal (ND) feeding.
Main Results:
- A significant reduction in apneic episodes was observed in 68.8% of neonates.
- The mean number of apneic episodes decreased significantly from 1.75 to 0.969 (P=.007).
- No serious adverse events were linked to transpyloric feeding.
Conclusions:
- Transpyloric feeding appears to be an effective therapeutic approach for selected preterm neonates experiencing reflux-associated apnea.
- This method demonstrates potential as a safe intervention for managing apnea in this specific neonatal population.
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