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Updated: Jul 23, 2025

Author Spotlight: Advancing Spectral Characterization of Physiological and Malperfused Tissues
Published on: July 5, 2024
Hepatic segmental arterial mediolysis: A case report and brief literature review
Ashbina Pokharel1, Ioannis Karageorgiou1, Sangam Shah2
1Department of Internal Medicine William Beaumont University Hospital Royal Oak Michigan USA.
Key Clinical Message:
When evaluating patients with abdominal pain, it is important to consider SAM in the differential diagnosis, along with vasculitis, fibromuscular dysplasia (FMD), atherosclerosis, mycotic aneurysms, and cystic medial degeneration.
Abstract:
Segmental arterial mediolysis (SAM) is a rare arteriopathy which is an under-recognized and commonly missed diagnosis of abdominal pain. We report a case of a 58-year-old female who presented with abdominal pain and was misdiagnosed with a urinary tract infection. The diagnosis was made with CTA and managed with embolization. Despite appropriate intervention and close hospital monitoring, further complications were inevitable. We conclude that though literature has shown better prognosis and even complete resolution after medical and/or surgical intervention, close follow up and monitoring is needed to avoid unexpected complications.

