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Updated: Jul 23, 2025
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Bioprinting of Cartilage and Skin Tissue Analogs Utilizing a Novel Passive Mixing Unit Technique for Bioink Precellularization
Published on: January 3, 2018
13.6K
Biomaterials / bioinks and extrusion bioprinting.
X B Chen1,2, A Fazel Anvari-Yazdi2, X Duan2
1Department of Mechanical Engineering, University of Saskatchewan, 57 Campus Dr, S7K 5A9, Saskatoon, Canada.
Bioactive Materials
|July 12, 2023
Summary
This review explores bioinks and extrusion bioprinting for creating 3D tissue constructs. It covers bioink properties, synthesis, characterization, and their impact on printing for tissue engineering and drug development.
Area of Science:
- Biomaterials Science
- Tissue Engineering
- Bioprinting Technologies
Background:
- Bioinks, formulations of cells and biomaterials, are crucial for 3D bioprinting.
- Extrusion bioprinting enables the deposition of bioinks to fabricate tissue constructs.
- These constructs are vital for regenerative medicine and in vitro drug testing.
Purpose of the Study:
- To critically review recent advancements in bioinks and biomaterial solutions for extrusion bioprinting.
- To analyze the synthesis, characterization, and properties of bioinks.
- To discuss the influence of bioink characteristics on the bioprinting process.
Main Methods:
- Literature review of current research on bioinks and extrusion bioprinting.
- Focus on bioink synthesis, rheological, mechanical, and biological property characterization.
- Analysis of the relationship between bioink properties and printing outcomes.
Main Results:
- Bioink properties significantly influence the success of extrusion bioprinting.
- Tailoring bioink formulations is key to achieving desired construct architectures and functionalities.
- Recent developments enhance control over bioink behavior during printing.
Conclusions:
- Optimizing bioink properties is essential for fabricating functional 3D tissue constructs.
- Further research is needed to address challenges in bioink development and bioprinting processes.
- Advancements in bioinks and extrusion bioprinting hold significant promise for tissue engineering and pharmaceutical applications.
