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Updated: Jul 23, 2025
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Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
Published on: January 25, 2016
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Comparative study of SSNHL with and without tinnitus: audiologic and hematologic differences
Jung Min Kim1, Hwa Sung Rim1, Sung Soo Kim2
1Department of Otorhinolaryngology, Head and Neck Surgery, College of Medicine, Kyung Hee University Hospital, Seoul, Republic of Korea.
Acta Oto-Laryngologica
|July 12, 2023
Summary
Tinnitus in sudden sensorineural hearing loss (SSNHL) is linked to specific auditory nerve and outer hair cell damage. Hematologic factors like monocyte and %LUCs percentages may also play a role in SSNHL patients with tinnitus.
Area of Science:
- Otolaryngology
- Audiology
- Neuroscience
Background:
- Tinnitus is a common symptom of sudden sensorineural hearing loss (SSNHL), affecting 60-90% of patients.
- Factors contributing to tinnitus in SSNHL are not well understood.
- This study investigates audiologic and hematologic differences between SSNHL patients with and without tinnitus.
Purpose of the Study:
- To compare audiologic and hematologic factors in SSNHL patients with and without tinnitus.
- To identify potential indicators for tinnitus development in SSNHL.
- To understand the relationship between tinnitus and SSNHL characteristics.
Main Methods:
- Compared 120 SSNHL patients with tinnitus to 59 SSNHL patients without tinnitus.
- Analyzed audiology (auditory brainstem response, otoacoustic emissions) and hematology test results.
- Assessed hearing recovery by comparing pre- and post-treatment hearing thresholds.
Main Results:
- Patients with tinnitus showed poorer auditory nerve and outer hair cell function (ABR, TEOAE, DPOAE).
- Tinnitus patients had worse hearing thresholds in the non-affected ear.
- Non-tinnitus patients had higher percentages of monocytes and large unstained cells (%LUCs).
Conclusions:
- Tinnitus in SSNHL may relate to baseline hearing, outer hair cell, and auditory nerve damage.
- Further research on hematologic data in SSNHL with tinnitus is warranted.
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