Recurrent cervical adenofibroma progressing to adenosarcoma: a rare case report.

Area of Science:

• Gynecologic Oncology
• Pathology
• Oncologic Imaging

Background:

• Cervical adenofibroma, a rare mixed mesodermal tumor, can manifest as recurrent cervical polyps.
• Progression to cervical adenosarcoma is uncommon but documented.
• Recurrent polypoidal masses necessitate thorough differential diagnosis.

Purpose of the Study:

• To report a case of cervical adenofibroma progressing to adenosarcoma.
• To emphasize the importance of differential diagnosis in recurrent cervical masses.
• To highlight the diagnostic challenges of cervical adenofibroma.

Main Methods:

• Case report of a patient with a 10-year history of recurrent cervical polypoidal mass.
• Diagnostic imaging included ultrasound and magnetic resonance imaging (MRI).
• Surgical pathology and immunohistochemistry confirmed cervical adenosarcoma after wide local excision via hysteroscopy.

Main Results:

• The patient presented with the eighth recurrence of a cervical polypoidal mass.
• Histopathological and immunohistochemical analysis confirmed the diagnosis of cervical adenosarcoma.
• Despite conservative management, the potential for recurrence and progression was noted.

Conclusions:

• Diagnosing cervical adenofibroma and differentiating it from adenosarcoma is challenging.
• Adenosarcoma must be excluded in cases of recurrent cervical polypoidal masses.
• A combined histological and immunohistochemical approach is essential for accurate diagnosis.