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Updated: Jul 23, 2025

Use of Galleria mellonella as a Model Organism to Study Legionella pneumophila Infection
Published on: November 22, 2013
Severe Cavitary Pneumonia Caused by Legionella pneumophila: a Case Report
Background:
Pulmonary cavities caused by Legionella occur mainly in immunocompromised patients, and clinical information in patients with normal immune function is therefore limited.
Methods:
We report a 64-year-old female who developed a Legionella pulmonary cavity without any immunological abnormality.
Results:
She suffered severe pneumonia complicated by acute respiratory failure and acute renal insufficiency. Despite long-term antibiotic therapy, she showed signs of a life-threatening infection and a progressive pulmonary cavity.
Conclusions:
Our case report provided clinical data regarding the diagnosis and therapy of patients who develop Legionella pulmonary cavities without any underlying disease.
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