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Related Concept Videos

Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

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Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
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Barrett Esophagus-II: Clinical Manifestations and Management01:21

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Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
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Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

Gastroesophageal Reflux Disease II: Clinical Features and Management

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Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
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Esophageal Varices-II: Clinical Features and Management01:28

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Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
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Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies01:28

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Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
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Esophageal Strictures-I: Introduction01:30

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Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
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Esophageal Lichen Planus: A Descriptive Multicenter Report.

Elizabeth S Aby1, Jason D Eckmann1, Jad Abimansour2

  • 1Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition.

Journal of Clinical Gastroenterology
|July 12, 2023
PubMed
Summary

Esophageal lichen planus (ELP) is a rare condition often missed. This study highlights its characteristics, frequent strictures, and varied treatments, emphasizing the need for better diagnostic suspicion and further research into effective therapies.

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Area of Science:

  • Gastroenterology
  • Dermatology
  • Immunology

Background:

  • Esophageal lichen planus (ELP) is a rare disorder frequently misdiagnosed.
  • Limited data exist on this patient population, primarily from small, single-center studies.

Purpose of the Study:

  • To characterize the clinical features, treatment strategies, and outcomes of patients with ELP.
  • To identify common endoscopic findings and management approaches for ELP.

Main Methods:

  • A multicenter, retrospective descriptive study was conducted.
  • Data from 7 US centers over a 5-year period (2015-2020) were analyzed.
  • Included 78 adult patients diagnosed with ELP.

Main Results:

  • The study included 78 patients (65 years old, 86% female, 90% Caucasian).
  • Over half had extraesophageal manifestations. Esophageal strictures (54%) and abnormal mucosa (50%) were common endoscopic findings.
  • Topical steroids and proton pump inhibitors were primary treatments; steroids showed better endoscopic response. Nearly half required treatment changes.

Conclusions:

  • A high index of suspicion and biopsy are crucial for diagnosing ELP, especially with extraesophageal involvement.
  • Effective therapies are limited and vary; prospective studies are needed to determine optimal treatment regimens.