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Glyoxal in hyperglycaemic ischemic stroke - a cohort study

Sina Rhein1,2, Julica Inderhees1,2,3, Oliver Herrmann4

  • 1Institute for Experimental and Clinical Pharmacology and Toxicology, Center for Brain, Behavior and Metabolism, University of Lübeck, Lübeck, Germany.

Cardiovascular Diabetology
|July 12, 2023
PubMed
Summary

High glucose levels in acute ischemic stroke are linked to poor outcomes. Reactive glucose metabolites, glyoxal and methylglyoxal, are associated with worse stroke prognosis, suggesting they may be therapeutic targets.

Keywords:
Advanced glycation end-productsGlucoseIschemic brain damageUndernutrition

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