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Measurement Properties of Patient Reported Outcome Scales: A Systematic Review

Emma Stallwood1, Ellen B M Elsman1, Andrea Monsour1

  • 1Child Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Toronto, Ontario, Canada.

Pediatrics
|July 13, 2023
PubMed

Insights

Patient-reported outcome measures (PROMs) like PROMIS show promise for pediatric care. The NIH Toolbox requires more research before clinical use.

Area of Science:

  • Pediatric Health Outcomes
  • Psychometrics
  • Clinical Measurement

Background:

  • A standard set of pediatric health outcomes, including patient-reported outcome measures (PROMs), was recently developed for routine care.
  • These PROMs cover global health, cognitive functioning, and self-efficacy in pediatric populations.

Purpose of the Study:

  • To evaluate the measurement properties of specific PROMs for use in routine pediatric care.
  • Specifically assessed were PROMIS Pediatric and Parent Proxy Scale - Global Health 7+2, PROMIS Parent Proxy Short Form - Cognitive Function 7a, and NIH Toolbox Self-Efficacy CAT Ages 13 to 17.

Main Methods:

  • Systematic review of literature using Embase, PsychINFO, Web of Science, and Medline databases.
  • Eligibility criteria included English, full-text, peer-reviewed articles evaluating the measurement properties of the selected PROMs.
  • The COSMIN guideline was utilized for study appraisal and evidence synthesis.

Main Results:

  • Four to six eligible studies were identified for each PROM after screening over 4000 titles.
  • PROMIS instruments demonstrated sufficient content validity (low-quality evidence) and structural validity/internal consistency (at least low-quality evidence).
  • The NIH Toolbox lacked essential evidence for content validity.

Conclusions:

  • PROMIS instruments possess adequate measurement properties for their intended constructs and age groups, supporting their use in pediatric routine care.
  • The NIH Toolbox requires further research, particularly on content validity, before clinical recommendation.
  • Underreporting in included studies may have influenced the assessment of measurement properties.
Abstract

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