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Risk Factors for the Development of Multisite Pain in Children

Chelsea M Kaplan1, Andrew Schrepf1, Kevin F Boehnke1

  • 1Department of Anesthesiology, Michigan Medicine, Ann Arbor, MI.

The Clinical Journal of Pain
|July 13, 2023
PubMed

Insights

Childhood multisite pain risk factors include female sex, sleep problems, and somatic symptoms. Early identification of these symptoms can aid in prevention strategies for youth experiencing pain.

Area of Science:

  • Pediatric Health
  • Pain Medicine
  • Developmental Psychology

Background:

  • Chronic pain poses significant economic burdens, comparable to major diseases.
  • Early onset of pain in childhood often leads to persistent adult pain.
  • Identifying predictive risk factors for pediatric multisite pain is crucial for effective intervention.

Purpose of the Study:

  • To investigate baseline symptom predictors of new-onset multisite pain in children.
  • To identify early warning signs for the development of chronic pain in youth.

Main Methods:

  • Longitudinal study analyzing symptom data from pain-free children (ages 9-10).
  • Multivariate logistic regression models used to assess risk factors.
  • Data collected from the Adolescent Brain Cognitive Development study.

Main Results:

  • Female sex, elevated nonpainful somatic symptoms, and sleep problems were associated with increased risk.
  • Attentional issues at baseline also predicted the development of multisite pain.
  • Negative affect was not found to be a significant predictor.

Conclusions:

  • Somatic awareness, sleep, and attention problems are key actionable targets for early detection.
  • These identified symptoms can inform prevention strategies for multisite pain in children.
  • Early intervention based on these risk factors may prevent the chronicity of pain.
Abstract

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