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Depression in the elderly: current management concepts.

R E Neshkes, L F Jarvik

    Geriatrics
    |September 1, 1986
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    Older adults can safely use antidepressants despite cardiovascular concerns. Physicians should start with low doses of desipramine, doxepin, or trazodone, prioritizing side effect profiles over efficacy for treatment selection.

    Area of Science:

    • Geriatric Medicine
    • Psychopharmacology
    • Cardiovascular Safety

    Background:

    • Physicians hesitate to prescribe antidepressants to older patients due to cardiovascular risk concerns.
    • This fear limits treatment options for a population that often requires antidepressant therapy.

    Purpose of the Study:

    • To advocate for the treatment of older patients with antidepressants.
    • To provide guidance on selecting appropriate antidepressant agents for geriatric populations.

    Main Methods:

    • Initiate treatment with low doses of specific antidepressants: desipramine, doxepin, or trazodone.
    • Consider patient tolerance to sedation and anticholinergic side effects when choosing a medication.

    Main Results:

    Related Experiment Videos

  • The study suggests that most older patients can be treated with antidepressants.
  • Drug selection should be guided by the side-effect profile, not efficacy differences.

    • Conclusions:

    • Antidepressant treatment is feasible and recommended for the majority of older patients.
    • Careful selection based on side effects ensures safer and more effective geriatric psychopharmacological management.