Quality indicators of hospitalized children influenced by clinical pharmacist services: A systematic review

Thaciana Dos Santos Alcântara1, Gabriela Andrade Conrado Carvalho1, Júlia Mirão Sanchez1

  • 1Laboratory of Teaching and Research in Social Pharmacy (LEPFS), Federal University of Sergipe, São Cristóvão, Sergipe, Brazil.

Insights

Pharmaceutical clinical services significantly improve pediatric hospital care by reducing hospital stay and readmissions. Key interventions include pharmacotherapy review, multidisciplinary team involvement, and antimicrobial stewardship programs, leading to better clinical and economic outcomes.

Area of Science:

  • Pediatric Hospital Pharmacy
  • Clinical Pharmacy Services
  • Healthcare Quality Improvement

Background:

  • Optimizing pediatric inpatient care requires rational medication use, driven by pharmacists and multidisciplinary teams.
  • Evaluating pharmaceutical clinical services through quality indicators is crucial for strategic decision-making.

Approach:

  • A systematic review was conducted, searching major databases (Cochrane, Embase, Lilacs, PubMed, Web of Science).
  • Studies evaluating the impact of pharmaceutical clinical services on clinical, economic, and humanistic outcomes were included.

Key Points:

  • Eleven studies were included, identifying four key pharmaceutical services: pharmacotherapy review, multiprofessional team interventions, antimicrobial stewardship programs, and discharge pharmaceutical services.
  • These services significantly reduced length of hospital stay (e.g., 6.45 days vs. 10.83 days with multiprofessional team interventions) and hospital readmissions (30-day reduction with antimicrobial stewardship).
  • Additional benefits included reduced hospital costs and improved caregiver satisfaction.

Conclusions:

  • Pharmacotherapy review, multiprofessional team interventions, and Antimicrobial Stewardship Programs demonstrably reduce length of hospital stay and hospital readmissions in pediatric patients.
  • These pharmaceutical interventions also lead to significant reductions in overall hospital costs.
  • The findings underscore the value of integrated pharmaceutical care in improving pediatric healthcare outcomes.
Abstract

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