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Arterial Hypertension-clinical trials update 2023
Felix Götzinger1, Michael Kunz2, Lucas Lauder2
1From the Department of Internal Medicine III, Cardiology, Angiology and Intensive Care Medicine, University Hospital Saarland, 66424, Homburg, Germany. felix.goetzinger@uks.eu.
This review highlights key 2022-2023 hypertension trial findings, including new treatments for resistant hypertension and optimal medication timing. It addresses blood pressure targets and novel device-based therapies for better cardiovascular outcomes.
Area of Science:
- Cardiology
- Nephrology
- Pharmacology
Background:
- Arterial hypertension significantly increases cardiovascular morbidity and mortality.
- Hypertension research is a dynamic and evolving field.
- Effective management strategies are crucial for patient outcomes.
Purpose of the Study:
- To summarize pivotal clinical trials in hypertension research from 2022 and early 2023.
- To present new findings on pharmacological and device-based treatments.
- To discuss optimal blood pressure targets and treatment inertia.
Main Methods:
- Review of major clinical trials published in 2022 and early 2023.
- Analysis of data on pharmacological interventions, including resistant hypertension.
- Inclusion of studies on pregnancy-related hypertension and post-stroke blood pressure management.
Main Results:
- New pharmacological approaches for resistant hypertension show promise.
- Optimal timing for antihypertensive medication intake is further elucidated.
- Novel device-based therapies are emerging as treatment options.
- Guideline inertia remains a challenge in blood pressure management.
Conclusions:
- Recent trials offer significant advancements in hypertension management.
- Optimizing treatment targets and addressing inertia are critical.
- Emerging therapies, including device-based interventions, expand treatment possibilities.
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