Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical Benefits of Established Cut-off Value for Thyroglobulin Washout Concentration Used for Selecting Patients for Lymphadenectomy Due to Cervical Lymph Node Metastases of Differentiated Thyroid Cancer.

Polski przeglad chirurgiczny·2026
Same author

Endoscopic Resection of Rectal Neuroendocrine Tumors: How Deep Should We Go?

Journal of clinical medicine·2026
Same author

Endoscopic ultrasound-guided Hartmann reversal procedure.

Endoscopy·2026
Same author

Comparative Early Postoperative Outcomes in Acute Calculous vs. Acute Acalculous Cholecystitis: A Retrospective Analysis.

Medicina (Kaunas, Lithuania)·2026
Same author

Analysis of correlation between RAD51 172G/T polymorphism and colorectal cancer in the Polish population.

Polski przeglad chirurgiczny·2026
Same author

Prognostic value of novel serological markers in predicting postoperative complications of ileocecal resection in Crohn's disease patients.

Polski przeglad chirurgiczny·2026

Related Experiment Video

Updated: Jul 23, 2025

Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer
12:45

Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer

Published on: February 12, 2022

5.7K

Rectal Cancer: Are 12 Lymph Nodes the Limit?

Paweł Mroczkowski1,2,3, Łukasz Dziki1, Tereza Vosikova2

  • 1Department for General and Colorectal Surgery, Medical University of Lodz, Pl. Hallera 1, 90-647 Lodz, Poland.

Cancers
|July 14, 2023
PubMed
Summary
This summary is machine-generated.

The 12-lymph node guideline for rectal cancer surgery is controversial. This study found that factors like T-stage and neoadjuvant therapy influence lymph node yield, and more examined nodes increase the chance of finding positive nodes.

Keywords:
abdominoperineal amputationlow anterior resectionlymph nodesrectal cancer

More Related Videos

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
08:26

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction

Published on: March 24, 2023

546
Quantification of Tumor Cell Adhesion in Lymph Node Cryosections
06:09

Quantification of Tumor Cell Adhesion in Lymph Node Cryosections

Published on: February 9, 2020

12.1K

Related Experiment Videos

Last Updated: Jul 23, 2025

Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer
12:45

Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer

Published on: February 12, 2022

5.7K
Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
08:26

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction

Published on: March 24, 2023

546
Quantification of Tumor Cell Adhesion in Lymph Node Cryosections
06:09

Quantification of Tumor Cell Adhesion in Lymph Node Cryosections

Published on: February 9, 2020

12.1K

Area of Science:

  • Oncology
  • Surgical Pathology
  • Gastrointestinal Surgery

Background:

  • Lymph node dissection is critical in rectal cancer surgery.
  • Current guidelines recommend a minimum of 12 lymph nodes for quality assessment, but this is debated.

Purpose of the Study:

  • To investigate factors affecting lymph node yield in rectal cancer.
  • To evaluate the validity of the 12-lymph node threshold.

Main Methods:

  • Analysis of 20,966 rectal cancer patients undergoing low anterior resection or abdominoperineal amputation (2000-2010).
  • Statistical analysis of factors influencing lymph node count and detection of positive nodes.

Main Results:

  • 20.53% of men and 19.31% of women had fewer than 12 lymph nodes.
  • T3 stage, female sex, risk factors, and neoadjuvant therapy significantly impacted lymph node yield.
  • A proportional relationship exists between examined nodes and positive node detection; no plateau was observed.

Conclusions:

  • The 12-lymph node count is a controversial quality metric for rectal cancer surgery.
  • Optimal surgical technique and pathological evaluation are paramount, not solely a numerical cutoff.
  • Factors beyond node count influence yield and detection of metastatic disease.