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MIRACUM-Pipe: An Adaptable Pipeline for Next-Generation Sequencing Analysis, Reporting, and Visualization for

Patrick Metzger1, Maria Elena Hess1,2, Andreas Blaumeiser1,3

  • 1Institute of Medical Bioinformatics and Systems Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, 79110 Freiburg, Germany.

Cancers
|July 14, 2023
PubMed

Keywords:
bioinformaticscomputational biologymolecular tumor boardnext-generation sequencingpipelineprecision oncologysoftwaresomatic variant callingworkflow

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Next-generation Sequencing03:00

Next-generation Sequencing

The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.