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Flow Dynamic Pattern in Liver and Renal Transplantation under Exercise Prescription Program
Marco Corsi1, Edoardo Falconi1, Roberto Palazzo1
1Sports Medicine Center, Clinical and Experimental Department, University of Florence, 50121 Florence, Italy.
Journal of Clinical Medicine
|July 14, 2023
Summary
Physically active solid-organ transplant recipients show better heart strain and diastolic function compared to sedentary individuals. Advanced echocardiography, like HyperDoppler, can detect early diastolic dysfunction before systolic issues arise.
Area of Science:
- Cardiology
- Transplant Medicine
- Medical Imaging
Background:
- Cardiovascular diseases are a major risk in transplant patients.
- Moderate physical activity can mitigate cardiovascular risks.
- Echocardiography, including vortex analysis, is crucial for assessing cardiotoxicity.
Purpose of the Study:
- To investigate intracardiac vortex parameters in physically active solid-organ transplant recipients.
- To compare these parameters with those of healthy subjects.
Main Methods:
- Transthoracic echocardiography was performed on 33 transplant recipients (16 kidney, 17 liver) and 17 healthy controls.
- Myocardial deformation parameters, including global longitudinal strain (GLS) and left ventricular (LV) twisting, were assessed.
- HyperDoppler imaging was utilized for dynamic flow analysis.
Main Results:
- Transplant recipients showed increased interventricular septum and posterior wall thickness, and LV mass index.
- Athletes, including transplanted individuals, had higher ejection fraction (EF).
- Physically active transplanted subjects demonstrated improved 4DStrain and GLS2c, with better diastolic function correlation to vorticity fluctuation.
Conclusions:
- Vortex analysis, particularly with normal EF, shows a correlation between diastolic parameters and flow dynamics.
- HyperDoppler imaging may enable earlier detection of diastolic dysfunction.
- This highlights the benefit of physical activity in managing cardiovascular health post-transplant.
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