Small Open Reading Frame-Encoded Micro-Peptides: An Emerging Protein World

Xiaoping Dong1,2, Kun Zhang3, Chengfeng Xun1,2

  • 1National & Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha 410081, China.

Summary

Small open reading frames (sORFs) encode small polypeptides (SEPs) previously dismissed as noise. Recent advances identify SEPs involved in crucial biological processes, opening new research avenues.

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