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Integration of Bioinformatics Approaches and Experimental Validations to Understand the Role of Notch Signaling in Ovarian Cancer
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CC Chemokine 2 Promotes Ovarian Cancer Progression through the MEK/ERK/MAP3K19 Signaling Pathway

Wei Liu1, Lei Wang1, Jiajia Zhang1

  • 1College of Life Sciences, Henan Agricultural University, Zhengzhou 450002, China.

International Journal of Molecular Sciences
|July 14, 2023
PubMed
Summary

Chemokine CCL2 promotes ovarian cancer progression and metastasis by upregulating MAP3K19 via the MEK/ERK pathway. Targeting CCL2 may offer a new therapeutic strategy for ovarian cancer.

Keywords:
CC-chemokine ligand 2MAPK/ERK pathwaymitogen-activated protein three kinase 19ovarian cancertumor progression

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