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Related Experiment Video

Updated: Jul 23, 2025

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model

Published on: June 18, 2021

Systemic Inflammation after Aneurysmal Subarachnoid Hemorrhage.

Chang-Zhang Chai¹, Ue-Cheung Ho², Lu-Ting Kuo^2,3

¹Department of Medical Education, National Taiwan University, School of Medicine, Taipei 100, Taiwan.

International Journal of Molecular Sciences

|July 14, 2023

Summary

Aneurysmal subarachnoid hemorrhage (aSAH) is a severe neurological condition. Systemic inflammation impacts outcomes, suggesting anti-inflammatory treatments may improve recovery for aSAH patients.

Keywords:

cerebral aneurysm subarachnoid hemorrhage systemic inflammation

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Last Updated: Jul 23, 2025

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model

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Published on: June 18, 2021

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Endovascular Perforation Model for Subarachnoid Hemorrhage Combined with Magnetic Resonance Imaging MRI

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Published on: December 16, 2021

Area of Science:

Neuroscience
Immunology
Neurology

Background:

Aneurysmal subarachnoid hemorrhage (aSAH) presents significant mortality and disability.
Systemic inflammation post-hemorrhagic stroke contributes to neurological damage.
Inflammatory biomarkers may predict clinical outcomes in aSAH.

Purpose of the Study:

To review the complex interplay between the nervous and immune systems in aSAH.
To explore the role of systemic inflammation in aSAH pathophysiology.
To discuss the potential of anti-inflammatory therapies for aSAH.

Main Methods:

Literature review of studies on aSAH, systemic inflammation, and neuroinflammation.
Analysis of biomarkers associated with aSAH outcomes.
Synthesis of current understanding of neuro-immune interactions in aSAH.

Main Results:

Systemic inflammation is a key factor in aSAH-related tissue damage.
Specific inflammatory markers correlate with patient prognosis.
The neuro-immune axis is critically involved in aSAH progression.

Conclusions:

Targeting systemic inflammation offers a promising therapeutic avenue for aSAH.
Understanding neuro-immune interactions is crucial for developing effective treatments.
Further research into anti-inflammatory strategies is warranted for improving aSAH outcomes.