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From Bench to Bedside: What Do We Know about Imidazothiazole Derivatives So Far?
Mu Guo1,2, Xiangbin Yu1,2, Yi Zhun Zhu3
1School of Pharmacy, Fujian Medical University, Fuzhou 350122, China.
Abstract:
Imidazothiazole derivatives are becoming increasingly important in therapeutic use due to their outstanding physiological activities. Recently, applying imidazothiazole as the core, researchers have synthesized a series of derivatives with biological effects such as antitumor, anti-infection, anti-inflammatory and antioxidant effects. In this review, we summarize the main pharmacological effects and pharmacological mechanisms of imidazothiazole derivates; the contents summarized herein are intended to advance the research and rational development of imidazothiazole-based drugs in the future.
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