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Related Concept Videos

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
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Factors Affecting the Risk of Infection01:26

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The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
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Inflammatory Response I: Vascular and Cellular01:30

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The inflammatory response is the body's defense against infection, injury, or irritation from bacteria, trauma, toxins, or heat. Inflammation helps locate and destroy pathogens and remove damaged tissue elements to heal the body. During this initial phase, fluid, blood products, and nutrients migrate to the injured area, resulting in redness, heat, swelling, ache, and loss of function. Moreover, signs of systemic inflammation include fever, increased WBC count, malaise, anorexia, nausea,...
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Inflammatory Response01:28

Inflammatory Response

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An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
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Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
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Inflammation01:38

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Related Experiment Video

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A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites
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Diet, Inflammation, and Infectious Diseases.

William B Grant1

  • 1Sunlight, Nutrition, and Health Research Center, P.O. Box 641603, San Francisco, CA 94164-1603, USA.

Nutrients
|July 14, 2023
PubMed
Summary

Diet significantly impacts inflammation and disease. This special issue explores how nutrition influences infectious and chronic disease progression and outcomes.

Area of Science:

  • Nutrition Science
  • Immunology
  • Infectious Diseases

Background:

  • Diet plays a crucial role in modulating host immune responses.
  • Inflammation is a key factor in the pathogenesis of many infectious and chronic diseases.
  • Understanding the diet-inflammation-disease nexus is vital for public health.

Discussion:

  • This Special Issue examines the intricate relationship between dietary patterns, inflammatory processes, and susceptibility to infectious and chronic diseases.
  • It highlights research on how specific nutrients and dietary components can influence immune cell function and inflammatory signaling pathways.
  • The collection addresses the impact of diet on outcomes for a range of conditions, from acute infections to long-term non-communicable diseases.

Key Insights:

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  • Dietary interventions show promise in managing inflammation associated with various diseases.
  • Specific dietary strategies can enhance immune defense against infectious agents.
  • Nutritional approaches may offer novel therapeutic avenues for chronic inflammatory conditions.

    • Outlook:

    • Further research is needed to elucidate precise mechanisms linking diet, inflammation, and disease.
    • Personalized nutrition strategies hold potential for optimizing health and disease prevention.
    • Translating research findings into public health guidelines is a critical next step.