Beta-adrenoreceptors determine affinity but not intrinsic activity of adenylate cyclase stimulants

Enhanced hypotensive, bradycardic, and hypnotic responses to alpha2-adrenergic agonists in spinophilin-null mice are accompanied by increased G protein coupling to the alpha2A-adrenergic receptor.

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Hetero-oligomers of alpha2A-adrenergic and mu-opioid receptors do not lead to transactivation of G-proteins or altered endocytosis profiles.

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The alpha(2a)-adrenergic receptor plays a protective role in mouse behavioral models of depression and anxiety.

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Dynamic sensitivity of ATP-sensitive K(+) channels to ATP.

The Journal of biological chemistry·2001

The role of a conserved inter-transmembrane domain interface in regulating alpha(2a)-adrenergic receptor conformational stability and cell-surface turnover.

Molecular pharmacology·2001

Agonist-regulated Interaction between alpha2-adrenergic receptors and spinophilin.

The Journal of biological chemistry·2001

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Related Experiment Videos

Beta-adrenoreceptors determine affinity but not intrinsic activity of adenylate cyclase stimulants

Related Concept Videos

Enhanced hypotensive, bradycardic, and hypnotic responses to alpha2-adrenergic agonists in spinophilin-null mice are accompanied by increased G protein coupling to the alpha2A-adrenergic receptor.

Hetero-oligomers of alpha2A-adrenergic and mu-opioid receptors do not lead to transactivation of G-proteins or altered endocytosis profiles.

The alpha(2a)-adrenergic receptor plays a protective role in mouse behavioral models of depression and anxiety.

Dynamic sensitivity of ATP-sensitive K(+) channels to ATP.

The role of a conserved inter-transmembrane domain interface in regulating alpha(2a)-adrenergic receptor conformational stability and cell-surface turnover.

Agonist-regulated Interaction between alpha2-adrenergic receptors and spinophilin.

Prehistoric global migration of vanishing gut microbes with humans.

A 7-eV bandgap semiconductor based on silicon-doped α-(AlxGa1-x)2O3.

A preinvasive regulatory T cell axis for lung cancer interception.

A thorium-229 optical nuclear clock with feedback loop.

Mechanism of spliceosome termination.

Retrofitting language models to operate over bytes.

Bile acid signaling in health and disease.

The physicochemical design, structure and permeability of the JCVI-syn3A minimal cell membrane.

Mechanisms of spatiotemporal regulation of transmembrane receptor turnover during directed cell migration.

Bioorthogonal chemistry for deciphering lipid biology in living systems.

Bile acids as a "new hormone" in aging-related liver disease.

Spatiotemporal modeling of GPCR signaling: The role of endosomal dynamics and receptor recycling.

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Beta-adrenoreceptors determine affinity but not intrinsic activity of adenylate cyclase stimulants

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