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Use of Lateral Flow Assays in Forensics.
Brigitte Bruijns1,2, Roald Tiggelaar3, Jaap Knotter1,2
1Technologies for Criminal Investigations, Saxion University of Applied Sciences, M.H. Tromplaan 28, 7513 AB Enschede, The Netherlands.
Lateral flow assays (LFAs) offer easy forensic analysis for drugs, DNA, and explosives. This review examines their development and challenges for crime scene application.
Area of Science:
- Forensic Science
- Analytical Chemistry
- Biotechnology
Background:
- Lateral flow assays (LFAs) are widely used in daily life.
- LFAs have been developed for forensic applications like drug, DNA, explosive, and body fluid analysis.
Purpose of the Study:
- To review academic developments of LFAs for forensic applications.
- To summarize the advantages and disadvantages of LFAs in various forensic fields.
- To critically assess the limited use of LFAs at crime scenes and identify barriers to market entry.
Main Methods:
- Literature review of academic research on LFAs for forensic science.
- Analysis of advantages and disadvantages for biological and chemical forensic applications.
- Critical evaluation of current limitations and future prospects for LFAs in forensic settings.
Main Results:
- LFAs show promise for forensic analysis due to ease-of-use.
- Specific applications include illicit drugs, DNA, explosives, and body fluid identification.
- Despite advantages, LFAs are not yet widely adopted at crime scenes.
Conclusions:
- LFAs offer significant potential for rapid forensic analysis.
- Barriers to widespread adoption at crime scenes need to be addressed.
- Further development and strategic market integration are required for LFAs in forensics.
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