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Treatment with Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors (PCSK9i): Current Evidence for Expanding the

Rosaria Vincenza Giglio1,2, Emir M Muzurović3,4, Angelo Maria Patti5

  • 1Department of Biomedicine, Neuroscience, and Advanced Diagnostics, Institute of Clinical Biochemistry, Clinical Molecular Medicine, and Laboratory Medicine, University of Palermo, Palermo, Italy.

Journal of Cardiovascular Pharmacology and Therapeutics
|July 14, 2023
PubMed
Summary

Proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9i) significantly lower LDL cholesterol, benefiting patients with high cardiovascular risk. These advanced therapies also show potential benefits for metabolic factors like nonalcoholic fatty liver disease.

Keywords:
atherosclerosislow-density lipoprotein cholesterollow-density lipoprotein receptornonalcoholic fatty liver diseaseproprotein convertase subtilisin/kexin type 9transaminase

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