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Challenges in treatment of gestational trophoblastic neoplasia in patients with MTHFR mutation: A case report

Jharna M Patel1, Danielle Glassman1, Sapna Sayal1

  • 1Rutgers Robert Wood Johnson Medical School, USA.

Gynecologic Oncology Reports
|July 14, 2023
PubMed

•We present a case of a patient with post molar pregnancy who has a MTHFR C677T mutation.•The mutation led to an alteration of recommended chemotherapy regimen.•No studies have reported treatment recommendations pertaining to gyn malignancies in patients with MTHFR allele.•We present a novel instance where MTHFR mutation altered a patient's treatment for gestational trophoblastic neoplasia.

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